Recombinant Human CNOT7 Protein, GST-tagged

• Cat.No.: CNOT7-1587H
• Product Overview: Human CNOT7 full-length ORF ( AAH60852, 1 a.a. - 285 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.09 kDa
• AA Sequence: MPAATVDHSQRICEVWACNLDEEMK KIRQVIRKYNYVAMDTEFPGVVARP IGEFRSNADYQYQLLRCNVDLLKII QLGLTFMNEQGEYPPGTSTWQFNFK FNLTEDMYAQDSIELLTTSGIQFKK HEEEGIETQYFAELLMTSGVVLCEG VKWLSFHSGYDFGYLIKILTNSNLP EEELDFFEILRLFFPVIYDVKYLMK SCKNLKGGLQEVAEQLELERIGPQH QAGSDSLLTGMAFFKMREMFFEDHI DDAKYCGHLYGLGSGSSYVQNGTGN AYEEEANKQS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CNOT7 CCR4-NOT transcription complex, subunit 7 [ Homo sapiens ]
• Official Symbol: CNOT7
• Synonyms: CNOT7; CCR4-NOT transcription complex, subunit 7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1 binding factor 1; CAF-1; BTG1-binding factor 1; CCR4-associated factor 1; carbon catabolite repressor protein (CCR4)-associative factor 1; hCAF-1
• Gene ID: 29883
• mRNA Refseq: NM_013354
• Protein Refseq: NP_037486
• MIM: 604913
• UniProt ID: Q9UIV1