Recombinant Human COQ3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human COQ3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : COQ3-5716H
Product Overview : COQ3 MS Standard C13 and N15-labeled recombinant protein (NP_059117) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 41 kDa
AA Sequence : MWSGRKLGSS GGWFLRVLGP GGCNTKAARP LISSAVYVKN QLSGTLQIKP GVFNEYRTIW FKSYRTIFSC LNRIKSFRYP WARLYSTSQT TVDSGEVKTF LALAHKWWDE QGVYAPLHSM NDLRVPFIRD NLLKTIPNHQ PGKPLLGMKI LDVGCGGGLL TEPLGRLGAS VIGIDPVDEN IKTAQCHKSF DPVLDKRIEY RVCSLEEIVE ETAETFDAVV ASEVVEHVID LETFLQCCCQ VLKPGGSLFI TTINKTQLSY ALGIVFSEQI AGIVPKGTHT WEKFVSPETL ESILESNGLS VQTVVGMLYN PFSGYWHWSE NTSLNYAAHA VKSRVQEHPA SAEFVLKGET EELQANACTN PAVHEKLKKT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : COQ3 coenzyme Q3, methyltransferase [ Homo sapiens (human) ]
Official Symbol : COQ3
Synonyms : COQ3; coenzyme Q3 homolog, methyltransferase (S. cerevisiae); coenzyme Q3 homolog, methyltransferase (yeast); hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; bA9819.1; polyprenyldihydroxybenzoate methyltransferase; DHHB-MT; DHHB-MTase; DHHB methyltransferase; methyltransferase COQ3; 2-polyprenyl-6-hydroxyphenyl methylase; 3-demethylubiquinone-10 3-methyltransferase; dihydroxyhexaprenylbenzoate methyltransferase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHBMT; DHHBMTASE; UG0215E05;
Gene ID : 51805
mRNA Refseq : NM_017421
Protein Refseq : NP_059117
MIM : 605196
UniProt ID : Q9NZJ6

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