Recombinant Human COX10 Protein, GST-tagged
| Cat.No. : | COX10-1732H |
| Product Overview : | Human COX10 full-length ORF ( AAH06394, 1 a.a. - 443 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
| Description : | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008] |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | GST |
| Molecular Mass : | 74.36 kDa |
| AA Sequence : | MAASPHTLSSRLLTGCVGGSVWYLE RRTIQDSPHKFLHLLRNVNKQWITF QHFSFLKRMYVTQLNRSHNQQVRPK PEPVASPFLEKTSSGQAKAEIYEMR PLSPPSLSLSRKPNEKELIELEPDS VIEDSIDVGKETKEEKRWKEMKLQV YDLPGILAQLSKIKLTALVVSTTAA GFALAPGPFDWPCFLLTSVGTGLAS CAANSINQFFEVPFDSNMNRTKNRP LVRGQISPLLAVSFATCCAVPGVAI LTLGVNPLTGALGLFNIFLYTCCYT PLKRISIANTWVGAVVGAIPPVMGW TAATGSLDAGAFLLGGILYSWQFPH FNALSWGLREDYSRGGYCMMSVTHP GLCRRVALRHCLALLVLSAAAPVLD ITTWTFPIMALPINAYISYLGFRFY VDADRRSSRRLFFCSLWHLPLLLLL MLTCKRPSGGGDAGPPPS |
| Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name : | COX10 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) [ Homo sapiens ] |
| Official Symbol : | COX10 |
| Synonyms : | COX10; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast); COX10 (yeast) homolog, cytochrome c oxidase assembly protein (heme A: farnesyltransferase); protoheme IX farnesyltransferase, mitochondrial; heme O synthase; heme A: farnesyltransferase; cytochrome c oxidase subunit X; cytochrome c oxidase assembly protein; |
| Gene ID : | 1352 |
| mRNA Refseq : | NM_001303 |
| Protein Refseq : | NP_001294 |
| MIM : | 602125 |
| UniProt ID : | Q12887 |
Products Types
| ◆ Recombinant Protein | ||
| COX10-805R | Recombinant Rhesus Macaque COX10 Protein, His (Fc)-Avi-tagged | +Inquiry |
| COX10-7606Z | Recombinant Zebrafish COX10 | +Inquiry |
| COX10-980R | Recombinant Rhesus monkey COX10 Protein, His-tagged | +Inquiry |
| COX10-2403C | Recombinant Chicken COX10 | +Inquiry |
| ◆ Lysates | ||
| COX10-387HCL | Recombinant Human COX10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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