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Recombinant Human CRADD Protein, GST-tagged

Cat.No. : CRADD-1831H
Product Overview : Human CRADD full-length ORF ( AAH37905, 1 a.a. - 199 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.63 kDa
AA Sequence : MEARDKQVLRSLRLELGAEVLVEGL VLQYVYEEGILTENHIQEINAQTTG LRKTMLLLDILPSRGPKAFDTFLDS LQEFPWVREKLKKAREEAMTDLPAG DRLTGIPSHILNSSPSDRQINQLAQ RLGPEWEPMVLSLGLSQTDIYRCKA NHPHNVQSQVVEAFIRWRQRFGKQA TFQSLHNGLRAVEVDPSLLLHMLE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CRADD CASP2 and RIPK1 domain containing adaptor with death domain [ Homo sapiens ]
Official Symbol : CRADD
Synonyms : CRADD; CASP2 and RIPK1 domain containing adaptor with death domain; death domain-containing protein CRADD; RAIDD; RIP associated ICH1/CED3 homologous protein with death domain; death adaptor molecule RAIDD; caspase and RIP adaptor with death domain; RIP-associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain; MRT34; MGC9163;
Gene ID : 8738
mRNA Refseq : NM_003805
Protein Refseq : NP_003796
MIM : 603454
UniProt ID : P78560

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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