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Active Recombinant Human CSF1 Protein, Animal Free

Cat.No. : CSF1-41H
Product Overview : Recombinant Human CSF1 Protein without tag was expressed in Human cells.
Animal Free and Xeno Free
  • Specification
  • Gene Information
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Description : M-CSF (Macrophage Colony stimulating Factor) is a hematopoietic stem cell factor and produced by various cell types including lymphocytes, fibroblasts, endothelial cells, myoblasts, monocytes, and osteoblasts. It is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells.
Source : Human cells
Species : Human
Bio-activity : The activity was measured by its ability to stimulate the proliferation of murine M-NFS-60 cells (Mouse Myeloid Leukemia indicator cell line).
Molecular Mass : 30-40 kDa
Endotoxin : <0.5 EU/ μg
Purity : High Purity, >95% by SDS-PAGE
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
Reconstitution : Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Gene Name : CSF1 colony stimulating factor 1 [ Homo sapiens (human) ]
Official Symbol : CSF1
Synonyms : CSF1; colony stimulating factor 1; MCSF; CSF-1; macrophage colony-stimulating factor 1; colony stimulating factor 1 (macrophage); lanimostim; macrophage colony stimulating factor 1; EC 2.7.10.1
Gene ID : 1435
mRNA Refseq : NM_000757
Protein Refseq : NP_000748
MIM : 120420
UniProt ID : P09603

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CSF1 affect cancer progression? 09/20/2022

CSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.

What are the potential side effects of CSF1 therapy? 07/11/2022

Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.

Can CSF1 therapy be combined with other treatments? 08/26/2020

Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.

What are the challenges in developing CSF1-based therapies? 09/26/2019

Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.

In what ways is CSF1 being researched for neurological disorders? 10/01/2018

Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.

Customer Reviews (3)

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Reviews
10/30/2017

    The CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.

    03/10/2017

      With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.

      06/09/2016

        Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.

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