Recombinant Human CSF1 protein, His-Avi-tagged

• Cat.No.: CSF1-603H
• Product Overview: Human CSF1 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Glu33-Asn190.

Specification

• Description: CSF-1, also known as M-CSF, is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 21.3KDa. Due to glycosylation, the protein migrates to 28- 34KDa based on Bis-Tris PAGE result.
• Protein length: Glu33-Asn190
• Endotoxin: Less than 0.1EU per ug by the LAL method.
• Purity: > 95% as determined by SDS-PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CSF1 colony stimulating factor 1 [Homo sapiens (human)]
• Official Symbol: CSF1
• Synonyms: colony stimulating factor 1 (macrophage); CSF1; CSF-1; Lanimostim; macrophage colony stimulating factor; macrophage colony-stimulating factor 1; MCSF; M-CSF; MCSFlanimostim; MGC31930
• Gene ID: 1435
• mRNA Refseq: NM_000757.6
• Protein Refseq: NP_000748.4
• MIM: 120420
• UniProt ID: P09603