Recombinant Human CSF1 protein, His/S-tagged CSF1-177H

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Recombinant Human CSF1 protein, His/S-tagged

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Cat.No. :	CSF1-177H
Product Overview :	Recombinant Human CSF1 fused with His/S tag was expressed in E. coli.
Description :	Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors.
Source :	E. coli
Species :	Human
Tag :	His/S
Form :	Lyophilized from sterile PBS, pH 7.4
Purity :	> 95 % as determined by SDS-PAGE
Storage :	Store at -70 centigrade. Avoid repeated freeze/thaw cycles.

Gene Name :	CSF1 colony stimulating factor 1 (macrophage) [ Homo sapiens ]
Official Symbol :	CSF1
Synonyms :	CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; M CSF; MCSF; MGC31930; lanimostim; CSF-1;
Gene ID :	1435
mRNA Refseq :	NM_000757
Protein Refseq :	NP_000748
MIM :	120420
UniProt ID :	P09603
Chromosome Location :	1p21-p13
Pathway :	Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Integrins in angiogenesis, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem;
Function :	cytokine activity; growth factor activity; growth factor activity; macrophage colony-stimulating factor receptor binding; macrophage colony-stimulating factor receptor binding; protein homodimerization activity;