Recombinant Human CX3CL1 Protein, His-Tagged

• Cat.No.: CX3CL1-01H
• Product Overview: Recombinant Human CX3CL1 Protein, His-Tagged was expressed in Baculovirus cell line

Specification

• Description: This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections.
• Source: Baculovirus
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 34.3 kDa
• Protein Length: 323aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by absorbance at 280nm)
• Storage Buffer: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: CX3CL1 C-X3-C motif chemokine ligand 1 [ Homo sapiens (human) ]
• Official Symbol: CX3CL1
• Synonyms: CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN, NTT, SCYD1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1
• Gene ID: 6376
• mRNA Refseq: NM_002996.6
• Protein Refseq: NP_002987.1
• MIM: 601880
• UniProt ID: P78423