Recombinant Rat CX3CL1 Protein, His (Fc)-Avi-tagged

• Cat.No.: CX3CL1-1342R
• Product Overview: Recombinant Rat CX3CL1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Rat
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Cx3cl1 chemokine (C-X3-C motif) ligand 1 [ Rattus norvegicus ]
• Official Symbol: CX3CL1
• Gene ID: 89808
• mRNA Refseq: NM_134455.1
• Protein Refseq: NP_604450.1
• UniProt ID: O55145

Reviews

03/15/2022

the CX3CL1 protein's compatibility with various experimental techniques further supports its usability.

08/06/2021

One of the standout features of the CX3CL1 protein is the excellent technical support provided by the manufacturer.

06/03/2021

Whether I need to study protein-protein interactions, protein localization, or protein folding, the CX3CL1 protein consistently delivers precise and meaningful data.

Q&As

In what ways is CX3CL1 linked to the modulation of pain perception and neuropathic pain conditions?

CX3CL1 is involved in pain modulation, and its dysregulation is associated with neuropathic pain conditions. Understanding its role may lead to the development of novel analgesic therapies.

Are there any ongoing clinical trials targeting CX3CL1 for therapeutic purposes?

Yes, several clinical trials are investigating the therapeutic potential of targeting CX3CL1 in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

In cardiovascular diseases, how does CX3CL1 impact inflammation and vascular function?

CX3CL1 contributes to inflammation in cardiovascular diseases and affects vascular function. Studying its role helps in understanding the pathophysiology of conditions like atherosclerosis.

How does CX3CL1 influence the recruitment and activation of immune cells in the context of inflammation?

CX3CL1 acts as a chemoattractant, facilitating the recruitment and activation of immune cells at the site of inflammation, playing a pivotal role in immune response regulation.

How is CX3CL1 being investigated for its potential as a biomarker in various diseases?

Researchers are exploring CX3CL1 as a potential biomarker for diseases such as rheumatoid arthritis and certain cancers, aiming to develop diagnostic tools and monitor disease progression.