Recombinant Human CYFIP1 Protein, GST-tagged

• Cat.No.: CYFIP1-2228H
• Product Overview: Human CYFIP1 partial ORF ( NP_055423.1, 735 a.a. - 819 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 35.09 kDa
• AA Sequence: GATIHLPPSNRYETLLKQRHVQLLG RSIDLNRLITQRVSAAMYKSLELAI GRFESEDLTSIVELDGLLEINRMTH KLLSRYLTLD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYFIP1 cytoplasmic FMR1 interacting protein 1 [ Homo sapiens ]
• Official Symbol: CYFIP1
• Synonyms: CYFIP1; cytoplasmic FMR1 interacting protein 1; cytoplasmic FMR1-interacting protein 1; cytoplasmic FMRP interacting protein 1; KIAA0068; P140SRA 1; selective hybridizing clone; SHYC; sra-1; specifically Rac1-associated protein 1; SRA1; P140SRA-1; FLJ45151
• Gene ID: 23191
• mRNA Refseq: NM_001033028
• Protein Refseq: NP_001028200
• MIM: 606322
• UniProt ID: Q7L576