Recombinant Human CYP2A6 Protein


Home / Products / Recombinant Proteins / Recombinant Human CYP2A6 Protein

Recombinant Human CYP2A6 Protein

CYP2A6 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CYP2A6-12H
Product Overview : Recombinant human CYP2A6 and human CYP-reductase without tag was coexpressed in Escherichia coli.
Amount: 0.5 nmol cytochrome P450
Description : This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
Source : E. coli
Species : Human
Bio-activity : Cytochrome c Reductase Activity: 263 nmol/min/mg protein
P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase])
Activity: Coumarin 7-hydroxylase
Linear with time up to: 8 min(Determined at 0.8 µM substrate, using a P450 concentration of 0.5 pmol/ml)
Linear with P450 up to: 2 pmol/ml(Determined at 0.8 µM substrate, using an incubation time of 5 min)
Vmax: 7.9 pmol/min/pmol CYP
Km: 0.88 µM
Usage : For laboratory (research) purposes only.
Storage : Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice.
Concentration : P450 Concentration: 1.0 nmol/ml
Protein Concentration: 10.0 mg/ml
Specific P450 Content: 100 pmol/mg protein
Storage Buffer : 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA
Gene Name : CYP2A6 cytochrome P450 family 2 subfamily A member 6 [ Homo sapiens (human) ]
Official Symbol : CYP2A6
Synonyms : CYP2A6; cytochrome P450 family 2 subfamily A member 6; CPA6; CYP2A; CYP2A3; P450PB; CYPIIA6; P450C2A; cytochrome P450 2A6; 1,4-cineole 2-exo-monooxygenase; coumarin 7-hydroxylase; cytochrome P450 IIA3; cytochrome P450(I); cytochrome P450, family 2, subfamily A, polypeptide 6; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6; flavoprotein-linked monooxygenase; xenobiotic monooxygenase; EC
Gene ID : 1548
mRNA Refseq : NM_000762
Protein Refseq : NP_000753
MIM : 122720
UniProt ID : P11509

Products Types

◆ Recombinant Protein

CYP2A6-2258HRecombinant Human CYP2A6 Protein, GST-tagged+Inquiry
CYP2A6-71HRecombinant Human CYP2A6 Protein+Inquiry
CYP2A6-126HRecombinant Human CYP2A6, MYC/DDK-tagged+Inquiry
CYP2A6-27019THRecombinant Human CYP2A6+Inquiry
CYP2A6-125HRecombinant Human CYP2A6+Inquiry

See All CYP2A6 Recombinant Protein

◆ Lysates

CYP2A6-7117HCLRecombinant Human CYP2A6 293 Cell Lysate+Inquiry

See All CYP2A6 Lysates

Related Gene


For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry

  • Note: There will be extra charge for optional service!

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy