Recombinant Human CYP39A1 Protein, GST-tagged

• Cat.No.: CYP39A1-2272H
• Product Overview: Human CYP39A1 full-length ORF ( AAH10358, 1 a.a. - 469 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.33 kDa
• AA Sequence: MELISPTVIIILGCLALFLLLQPKN LRRPPCIKGWIPWIGVGFEFGKAPL EFIEKARIKYGPIFTVFAMGNRMTF VTEEEGINVFLKSKKVDFELAVQNI VYRTASIPKNVFLALHEKLYIMLKG KMGTVNLHQFTGQLTEELHEQLENL GTHGTMDLNNLVRHLLYPVTVNMLF NKSLFSTNKKKIKEFHQYFQVYDED FEYGSQLPECLLRNWSKSKKWFLEL FEKNIPDIKACKSAKDNSMTLLQAT LDIVETETSKENSPNYGLLLLWASL SNAVPVAFWTLAHVLSHPDIHKAIM EGISSVFGKAGKDKIKVSEDDLENL LLIKWCVLETIRLKAPGVITRKVVK PVEILNYIIPSGDLLMLSPFWLHRN PKYFPEPELFKPERWKKANLEKHSF LDCFMAFGSGKFQCPARWFALLEVQ MCIILILYKYDCSLLDPLPKQSYLH LVGVPQPEGQCRIEYKQRI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 [ Homo sapiens ]
• Official Symbol: CYP39A1
• Synonyms: CYP39A1; cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha hydroxylase), polypeptide 1; 24-hydroxycholesterol 7-alpha-hydroxylase; hCYP39A1; cytochrome P450 39A1; oxysterol 7alpha-hydroxylase; oxysterol 7-alpha-hydroxylase; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1
• Gene ID: 51302
• mRNA Refseq: NM_016593
• Protein Refseq: NP_057677
• MIM: 605994
• UniProt ID: Q9NYL5