| Description : |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
57.3 kDa |
| AA Sequence : |
MAAAAGMLLLGLLQAGGSVLGQAME KVTGGNLLSMLLIACAFTLSLVYLI RLAAGHLVQLPAGVKSPPYIFSPIP FLGHAIAFGKSPIEFLENAYEKYGP VFSFTMVGKTFTYLLGSDAAALLFN SKNEDLNAEDVYSRLTTPVFGKGVA YDVPNPVFLEQKKMLKSGLNIAHFK QHVSIIEKETKEYFESWGESGEKNV FEALSELIILTASHCLHGKEIRSQL NEKVAQLYADLDGGFSHAAWLLPGW LPLPSFRRRDRAHREIKDIFYKAIQ KRRQSQEKIDDILQTLLDATYKDGR PLTDDEVAGMLIGLLLAGQHTSSTT SAWMGFFLARDKTLQKKCYLEQKTV CGENLPPLTYDQLKDLNLLDRCIKE TLRLRPPVMIMMRMARTPQTVAGYT IPPGHQVCVSPTVNQRLKDSWVERL DFNPDRYLQDNPASGEKFAYVPFGA GRHRCIGENFAYVQIKTIWSTMLRL YEFDLIDGYFPTVNYTTMIHTPENP VIRYKRRSKTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
