Recombinant Human CYTH1, His-tagged

• Cat.No.: CYTH1-85H
• Product Overview: Recombinant human CYTH1 was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: CYTH1 also known as Cytohesin1 isofiorm1. CYTH1 promotes guanine-nucleotide exchange on ARF1 and ARF5 also promotes the activation of ARF factors through replacement of GDP with GTP.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT
• Molecular Mass: 48.8 kDa (421aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEEDDSY VPSDLTAEER QELENIRRRK QELLADIQRL KDEIAEVANE IENLGSTEER KNMQRNKQVA MGRKKFNMDP KKGIQFLIEN DLLKNTCEDI AQFLYKGEGL NKTAIGDYLG ERDEFNIQVL HAFVELHEFT DLNLVQALRQ FLWSFRLPGE AQKIDRMMEA FAQRYCQCNN GVFQSTDTCY VLSFAIIMLN TSLHNPNVKD KPTVERFIAM NRGINDGGDL PEELLRNLYE SIKNEPFKIP EDDGNDLTHT FFNPDREGWL LKLGGGRVKT WKRRWFILTD NCLYYFEYTT DKEPRGIIPL ENLSIREVED SKKPNCFELY IPDNKDQVIK ACKTEADGRV VEGNHTVYRI SAPTPEEKEE WIKCIKAAIS RDPFYEMLAA RKKKVSSTKR H
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CYTH1 cytohesin 1 [ Homo sapiens ]
• Official Symbol: CYTH1
• Synonyms: CYTH1; cytohesin 1; pleckstrin homology, Sec7 and coiled coil domains 1 , PSCD1; cytohesin-1; B2 1; D17S811E; cytoadhesin 1; SEC7 homolog B2-1; homolog of secretory protein SEC7; pleckstrin homology, Sec7 and coiled-coil domains 1; PH, SEC7 and coiled-coil domain-containing protein 1; B2-1; SEC7; PSCD1; CYTOHESIN-1; FLJ34050; FLJ41900
• Gene ID: 9267
• mRNA Refseq: NM_004762
• Protein Refseq: NP_004753
• MIM: 182115
• UniProt ID: Q15438
• Chromosome Location: 17q25
• Pathway: Class I PI3K signaling events, organism-specific biosystem
• Function: ARF guanyl-nucleotide exchange factor activity; protein binding