Recombinant Human DCP2 cell lysate

• Cat.No.: DCP2-446HCL

Specification

• Species: Human
• Tag: Non
• Description: DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: DCP2 DCP2 decapping enzyme homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DCP2
• Synonyms: DCP2; DCP2 decapping enzyme homolog (S. cerevisiae); mRNA-decapping enzyme 2; nudix (nucleoside diphosphate linked moiety X) type motif 20; NUDT20; hDpc; nudix (nucleoside diphosphate linked moiety X)-type motif 20; FLJ33245
• Gene ID: 167227
• mRNA Refseq: NM_001242377
• Protein Refseq: NP_001229306
• MIM: 609844
• UniProt ID: Q8IU60
• Chromosome Location: 5q22
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Decapping complex, organism-specific biosystem; Decapping complex, conserved biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem
• Function: RNA binding; exoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; manganese ion binding; metal ion binding; protein binding