Recombinant Human DMP1 Protein (17-513 aa), His-tagged

• Cat.No.: DMP1-2398H
• Product Overview: Recombinant Human DMP1 Protein (17-513 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.

Specification

• Description: May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 56.0 kDa
• Protein length: 17-513 aa
• AA Sequence: LPVTRYQNNESEDSEEWKGHLAQAP TPPLESSESSEGSKVSSEEQANEDP SDSTQSEEGLGSDDHQYIYRLAGGF SRSTGKGGDDKDDDEDDSGDDTFGD DDSGPGPKDRQEGGNSRLGSDEDSD DTIQASEESAPQGQDSAQDTTSESR ELDNEDRVDSKPEGGDSTQESESEE HWVGGGSDGESSHGDGSELDDEGMQ SDDPESIRSERGNSRMNSAGMKSKE SGENSEQANTQDSGGSQLLEHPSRK IFRKSRISEEDDRSELDDNNTMEEV KSDSTENSNSRDTGLSQPRRDSKGD SQEDSKENLSQEESQNVDGPSSESS QEANLSSQENSSESQEEVVSESRGD NPDPTTSYVEDQEDSDSSEEDSSHT LSHSKSESREEQADSESSESLNFSE ESPESPEDENSSSQEGLQSHSSSAE SQSEESHSEEDDSDSQDSSRSKEDS NSTESKSSSEEDGQLKNIEIESRKL TVDAYHNKPIGDQDDNDCQDGY
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: DMP1 dentin matrix acidic phosphoprotein 1 [ Homo sapiens ]
• Official Symbol: DMP1
• Synonyms: DMP1; dentin matrix acidic phosphoprotein 1; dentin matrix protein 1; ARHP; ARHR; DMP-1
• Gene ID: 1758
• mRNA Refseq: NM_001079911
• Protein Refseq: NP_001073380
• MIM: 600980
• UniProt ID: Q13316