Recombinant Human DNM2 Protein, GST-tagged
Cat.No. : | DNM2-2786H |
Product Overview : | Human DNM2 full-length ORF ( NP_001005360.1, 1 a.a. - 870 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 124.5 kDa |
AA Sequence : | MGNRGMEELIPLVNKLQDAFSSIGQ SCHLDLPQIAVVGGQSAGKSSVLEN FVGRDFLPRGSGIVTRRPLILQLIF SKTEHAEFLHCKSKKFTDFDEVRQE IEAETDRVTGTNKGISPVPINLRVY SPHVLNLTLIDLPGITKVPVGDQPP DIEYQIKDMILQFISRESSLILAVT PANMDLANSDALKLAKEVDPQGLRT IGVITKLDLMDEGTDARDVLENKLL PLRRGYIGVVNRSQKDIEGKKDIRA ALAAERKFFLSHPAYRHMADRMGTP HLQKTLNQQLTNHIRESLPALRSKL QSQLLSLEKEVEEYKNFRPDDPTRK TKALLQMVQQFGVDFEKRIEGSGDQ VDTLELSGGARINRIFHERFPFELV KMEFDEKDLRREISYAIKNIHGVRT GLFTPDLAFEAIVKKQVVKLKEPCL KCVDLVIQELINTVRQCTSKLSSYP RLREETERIVTTYIREREGRTKDQI LLLIDIEQSYINTNHEDFIGFANAQ QRSTQLNKKRAIPNQGEILVIRRGW LTINNISLMKGGSKEYWFVLTAESL SWYKDEEEKEKKYMLPLDNLKIRDV EKGFMSNKHVFAIFNTEQRNVYKDL RQIELACDSQEDVDSWKASFLRAGV YPEKDQAENEDGAQENTFSMDPQLE RQVETIRNLVDSYVAIINKSIRDLM PKTIMHLMINNTKAFIHHELLAYLY SSADQSSLMEESADQAQRRDDMLRM YHALKEALNIIGDISTSTVSTPVPP PVDDTWLQSASSHSPTPQRRPVSSI HPPGRPPAVRGPTPGPPLIPVPVGA AASFSAPPIPSRPGPQSVFANSDLF PAPPQIPSRPVRIPPGIPPGVPSRR PPAAPSRPTIIRPAEPSLLD |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DNM2 dynamin 2 [ Homo sapiens ] |
Official Symbol : | DNM2 |
Synonyms : | DNM2; dynamin 2; dynamin-2; CMTDI1; CMTDIB; cytoskeletal protein; DI CMTB; DYN2; dynamin II; DYNII; CMT2M; DI-CMTB; |
Gene ID : | 1785 |
mRNA Refseq : | NM_001005360 |
Protein Refseq : | NP_001005360 |
MIM : | 602378 |
UniProt ID : | P50570 |
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◆ Lysates | ||
DNM2-6857HCL | Recombinant Human DNM2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionDNM2 interacts with β-actin.
DNM2 is closely associated with the study of chronic heart failure and chronic progressive extraocular muscle paralysis in the elderly.
DNM2 gene is widely expressed in various mammalian tissues.
DNM1 and DNM3 are all homologs of DNM2.
DNM2 is involved in the regulation of Golgi reticular system transport, mitochondrial fusion, cytoplasmic division and synaptic vesicle endocytosis.
N-terminal GTPase structural domain, intermediate domain, PH structural domain, GTPase effector structural domain, and C-terminal proline- and arginine-rich domain.
Customer Reviews (3)
Write a reviewDNM2 proteins purchased are as advertised and the quality of the product is guaranteed.
Excellent after-sales service, solving many experimental problems.
The technician gave me a thorough introduction to the DNM2 protein so that I could understand its biochemical properties.
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