Recombinant Human DOC2B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DOC2B-5574H
• Product Overview: DOC2B MS Standard C13 and N15-labeled recombinant protein (NP_003576) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.8 kDa
• AA Sequence: MTLRRRGEKATISIQEHMAIDVCPG PIRPIKQISDYFPRFPRGLPPDAGP RAAAPPDAPARPAVAGAGRRSPSDG AREDDEDVDQLFGAYGSSPGPSPGP SPARPPAKPPEDEPDADGYESDDCT ALGTLDFSLLYDQENNALHCTITKA KGLKPMDHNGLADPYVKLHLLPGAS KANKLRTKTLRNTLNPTWNETLTYY GITDEDMIRKTLRISVCDEDKFRHN EFIGETRVPLKKLKPNHTKTFSICL EKQLPVDKTEDKSLEERGRILISLK YSSQKQGLLVGIVRCAHLAAMDANG YSDPYVKTYLRPDVDKKSKHKTAVK KKTLNPEFNEEFCYEIKHGDLAKKS LEVTVWDYDIGKSNDFIGGVVLGIH AKGERLKHWFDCLKNKDKRIERWHT LTSELPGAVLSDTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DOC2B double C2 domain beta [ Homo sapiens (human) ]
• Official Symbol: DOC2B
• Synonyms: DOC2B; double C2-like domains, beta; DOC2BL, double C2 like domains, beta like; double C2-like domain-containing protein beta; doc2-beta; DOC2BL
• Gene ID: 8447
• mRNA Refseq: NM_003585
• Protein Refseq: NP_003576
• MIM: 604568
• UniProt ID: Q14184