Recombinant Human DPH3 Protein, Myc/DDK-tagged, C13 and N15-labeled DPH3-1992H

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Recombinant Human DPH3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	DPH3-1992H
Product Overview :	DPH3 MS Standard C13 and N15-labeled recombinant protein (NP_996662) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	9.2 kDa
AA Sequence :	MAVFHDEVEI EDFQYDEDSE TYFYPCPCGD NFSITKEDLE NGEDVATCPS CSLIIKVIYD KDQFVCGETV PAPSANKELV KCTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	DPH3 diphthamide biosynthesis 3 [ Homo sapiens (human) ]
Official Symbol :	DPH3
Synonyms :	DESR1; DPH3A; KTI11; ZCSL2; DELGIP; DELGIP1
Gene ID :	285381
mRNA Refseq :	NM_206831
Protein Refseq :	NP_996662
MIM :	608959
UniProt ID :	Q96FX2