Recombinant Human DPM1 Protein, GST-tagged

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Recombinant Human DPM1 Protein, GST-tagged

DPM1 Related Products

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Cat.No. : DPM1-2836H
Product Overview : Human DPM1 full-length ORF ( AAH08466.1, 1 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 56 kDa
AA Sequence : MASLEVSRGP RRSRRELEVR SPRQNKYSVL LPTYNERENL PLIVWLLVKS FSESGINYEI IIIDDGSPDG TRDVAEQLEK IYGSDRILLR PREKKLGLGT AYIHGMKHAT GNYIIIMDAD LSHHPKFIPE FIRKQKEGNF DIVSGTRYKG NGGVYGWDLK RKIISRGANF LTQILLRPGA SDLTGSFRLY RKEVLEKLIE KCVSKGYVFQ MEMIVRARQM NYTIGEVPIS FVDRVYGESK LGGNEIVSFL KGLLTLFATT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit [ Homo sapiens ]
Official Symbol : DPM1
Synonyms : DPM1; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; dolichol-phosphate mannosyltransferase; CDGIE; MPDS; DPM synthase; MPD synthase; mannose-P-dolichol synthase; dolichol-phosphate mannose synthase; dolichol monophosphate mannose synthase; dolichyl-phosphate beta-D-mannosyltransferase;
Gene ID : 8813
mRNA Refseq : NM_003859
Protein Refseq : NP_003850
MIM : 603503
UniProt ID : O60762
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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