"DPM1" Related Products

Recombinant Human DPM1 Protein, GST-tagged

Cat.No. : DPM1-2836H
Product Overview : Human DPM1 full-length ORF ( AAH08466.1, 1 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 56 kDa
AA Sequence : MASLEVSRGPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRGANFLTQILLRPGASDLTGSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQMNYTIGEVPISFVDRVYGESKLGGNEIVSFLKGLLTLFATT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit [ Homo sapiens ]
Official Symbol : DPM1
Synonyms : DPM1; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; dolichol-phosphate mannosyltransferase; CDGIE; MPDS; DPM synthase; MPD synthase; mannose-P-dolichol synthase; dolichol-phosphate mannose synthase; dolichol monophosphate mannose synthase; dolichyl-phosphate beta-D-mannosyltransferase;
Gene ID : 8813
mRNA Refseq : NM_003859
Protein Refseq : NP_003850
MIM : 603503
UniProt ID : O60762

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