| Description : |
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
96.4 kDa |
| AA Sequence : |
MATTGTPTADRGDAAATDDPAARFQ VQKHSWDGLRSIIHGSRKYSGLIVN KAPHDFQFVQKTDESGPHSHRLYYL GMPYGSRENSLLYSEIPKKVRKEAL LLLSWKQMLDHFQATPHHGVYSREE ELLRERKRLGVFGITSYDFHSESGL FLFQASNSLFHCRDGGKNGFMVSPM KPLEIKTQCSGPRMDPKICPADPAF FSFINNSDLWVANIETGEERRLTFC HQGLSNVLDDPKSAGVATFVIQEEF DRFTGYWWCPTASWEGSEGLKTLRI LYEEVDESEVEVIHVPSPALEERKT DSYRYPRTGSKNPKIALKLAEFQTD SQGKIVSTQEKELVQPFSSLFPKVE YIARAGWTRDGKYAWAMFLDRPQQW LQLVLLPPALFIPSTENEEQRLASA RAVPRNVQPYVVYEEVTNVWINVHD IFYPFPQSEGEDELCFLRANECKTG FCHLYKVTAVLKSQGYDWSEPFSPG EDEFKCPIKEEIALTSGEWEVLARH GSKGTKDTPLEHHLYVVSYEAAGEI VRLTTPGFSHSCSMSQNFDMFVSHY SSVSTPPCVHVYKLSGPDDDPLHKQ PRFWASMMEAASCPPDYVPPEIFHF HTRSDVRLYGMIYKPHALQPGKKHP TVLFVYGGPQVQLVNNSFKGIKYLR LNTLASLGYAVVVIDGRGSCQRGLR FEGALKNQMGQVEIEDQVEGLQFVA EKYGFIDLSRVAIHGWSYGGFLSLM GLIHKPQVFKVAIAGAPVTVWMAYD TGYTERYMDVPENNQHGYEAGSVAL HVEKLPNEPNRLLILHGFLDENVHF FHTNFLVSQLIRAGKPYQLQIYPNE RHSIRCPESGEHYEVTLLHFLQEYL TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
