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Recombinant Human DPYD Protein, GST-tagged

Cat.No. : DPYD-2860H
Product Overview : Human DPYD full-length ORF ( AAH08379, 1 a.a. - 173 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 44.66 kDa
AA Sequence : MAPVLSKDSADIESILALNPRTQTH ATLCSTSAKKLDKKHWKRNPDKNCF NCEKLENNFDDIKHTTLGERGALRE AMRCLKCADAPCQKSCPTNLDIKSF ITSIANKNYYGAAKMIFSDNPLGLT CGMVCPTSDLCVGGCNLYATEEGPI NIGGLQQFATETLILAFSLMNHL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DPYD dihydropyrimidine dehydrogenase [ Homo sapiens ]
Official Symbol : DPYD
Synonyms : DPYD; dihydropyrimidine dehydrogenase; dihydropyrimidine dehydrogenase [NADP(+)]; DPD; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase; DHP; DHPDHASE; MGC70799; MGC132008;
Gene ID : 1806
mRNA Refseq : NM_000110
Protein Refseq : NP_000101
MIM : 612779
UniProt ID : Q12882

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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