Recombinant Human DSC2 Protein, MYC/DDK-tagged

• Cat.No.: DSC2-2527H
• Product Overview: Recombinant Human DSC2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 97 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DSC2 desmocollin 2 [ Homo sapiens ]
• Official Symbol: DSC2
• Synonyms: ARVD11; CDHF2; DG2; DGII/III; DSC3
• Gene ID: 1824
• mRNA Refseq: NM_004949
• Protein Refseq: NP_004940
• MIM: 125645
• UniProt ID: Q02487