Recombinant Human DSG4, GST-tagged

• Cat.No.: DSG4-12180H
• Product Overview: Recombinant Human DSG4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 855-1040a.a.
• Description: This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DSG4 desmoglein 4 [ Homo sapiens ]
• Official Symbol: DSG4
• Synonyms: DSG4; desmoglein 4; desmoglein-4; CDHF13; LAH; CDH family member 13; cadherin family member 13; CDGF13
• Gene ID: 147409
• mRNA Refseq: NM_001134453
• Protein Refseq: NP_001127925
• MIM: 607892
• UniProt ID: Q86SJ6
• Chromosome Location: 18q12.1
• Function: calcium ion binding