Recombinant Human DUS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DUS2 Protein, Myc/DDK-tagged, C13 and N15-labeled

DUS2 Related Products

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Cat.No. : DUS2-3072H
Product Overview : DUS2L MS Standard C13 and N15-labeled recombinant protein (NP_060273) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 55.1 kDa
AA Sequence : MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL STVDFVAPDD RVVFRTCERE QNRVVFQMGT SDAERALAVA RLVENDVAGI DVNMGCPKQY STKGGMGAAL LSDPDKIEKI LSTLVKGTRR PVTCKIRILP SLEDTLSLVK RIERTGIAAI AVHGRKREER PQHPVSCEVI KAIADTLSIP VIANGGSHDH IQQYSDIEDF RQATAASSVM VARAAMWNPS IFLKEGLRPL EEVMQKYIRY AVQYDNHYTN TKYCLCQMLR EQLESPQGRL LHAAQSSREI CEAFGLGAFY EETTQELDAQ QARLSAKTSE QTGEPAEDTS GVIKMAVKFD RRAYPAQITP KMCLLEWCRR EKLAQPVYET VQRPLDRLFS SIVTVAEQKY QSTLWDKSKK LAEQAAAIVC LRSQGLPEGR LGEESPSLHK RKREAPDQDP GGPRAQELAQ PGDLCKKPFV ALGSGEESPL EGWTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DUS2 dihydrouridine synthase 2 [ Homo sapiens (human) ]
Official Symbol : DUS2
Synonyms : DUS2; dihydrouridine synthase 2; SMM1; DUS2L; URLC8; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; SMM1 homolog; dihydrouridine synthase 2-like, SMM1 homolog; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); up-regulated in lung cancer protein 8; EC 1.3.1.91
Gene ID : 54920
mRNA Refseq : NM_017803
Protein Refseq : NP_060273
MIM : 609707
UniProt ID : Q9NX74

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