Recombinant Human DUSP16, GST-tagged

• Cat.No.: DUSP16-102H
• Product Overview: The protein was expressed as gst-tagged fusion protein by E.Coli and puri?ed by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.
• AA Sequence: 313-662aa
• Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freezethaw cycles should be avoided.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DUSP16 dual specificity phosphatase 16 [ Homo sapiens (human) ]
• Official Symbol: DUSP16
• Synonyms: DUSP16; MKP7; MKP-7; dual specificity phosphatase 16; MAPK phosphatase-7; MAP kinase phosphatase 7; mitogen-activated protein kinase phosphatase 7; EC 3.1.3.16; EC 3.1.3.48
• Gene ID: 80824
• mRNA Refseq: NM_030640
• Protein Refseq: NP_085143
• MIM: 607175
• UniProt ID: Q9BY84
• Chromosome Location: 12p13
• Pathway: MAPK signaling pathway; Regulation of p38-alpha and p38-beta
• Function: MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity; protein tyrosine phosphatase activity