"DUSP5" Related Products

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Recombinant Human DUSP5 Protein, His-tagged

Cat.No.: DUSP5-382H
Product Overview: Recombinant Human DUSP5(Met1~Glu135) fused with His tag at N-terminal was expressed in E. coli.
Description: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Source: E. coli
Species: Human
Tag : His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 18.4kDa
Protein length: Met1~Glu135
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: DUSP5 dual specificity phosphatase 5 [ Homo sapiens ]
Official Symbol: DUSP5
Synonyms: DUSP5; dual specificity phosphatase 5; dual specificity protein phosphatase 5; HVH3; VH1-like phosphatase 3; dual specificity protein phosphatase hVH3; serine/threonine specific protein phosphatase; DUSP;
Gene ID: 1847
mRNA Refseq: NM_004419
Protein Refseq: NP_004410
MIM: 603069
UniProt ID: Q16690

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