Recombinant Human DUX4 Protein, GST-tagged
Cat.No. : | DUX4-2957H |
Product Overview : | Human DUX4 full-length ORF (AAI60122.1, 1 a.a. - 424 a.a.) recombinant protein with GST tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 73.1 kDa |
AA Sequence : | MALPTPSDSTLPAEARGRGRRRRLV WTPSQSEALRACFERNPYPGIATRE RLAQAIGIPEPRVQIWFQNERSRQL RQHRRESRPWPGRRGPPEGRRKRTA VTGSQTALLLRAFEKDRFPGIAARE ELARETGLPESRIQIWFQNRRARHP GQGGRAPAQAGGLCSAAPGGGHPAP SWVAFAHTGAWGTGLPAPHVPCAPG ALPQGAFVSQAARAAPALQPSQAAP AEGVSQPAPARGDFAYAAPAPPDGA LSHPQAPRWPPHPGKSREDRDPQRD GLPGPCAVAQPGPAQAGPQGQGVLA PPTSQGSPWWGWGRGPQVAGAAWEP QAGAAPPPQPAPPDASASARQGQMQ GIPAPSQALQEPAPWSALPCGLLLD ELLASPEFLQQAQPLLETEAPGELE ASEEAASLEAPLSEEEYRALLEEL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | DUX4 double homeobox 4 [ Homo sapiens ] |
Official Symbol : | DUX4 |
Synonyms : | DUX4; double homeobox 4; double homeobox protein 4; double homeobox protein 10; double homeobox protein 4/10; double homeobox protein DUX10; DUX10; |
Gene ID : | 22947 |
mRNA Refseq : | NM_033178 |
Protein Refseq : | NP_149418 |
MIM : | 606009 |
UniProt ID : | Q9UBX2 |
Products Types
◆ Recombinant Protein | ||
DUX4-2958H | Recombinant Human DUX4 Protein, GST-tagged | +Inquiry |
DUX4-5857H | Recombinant Human DUX4 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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