Recombinant Human Dynein, Axonemal, Light Chain 4, His-tagged

• Cat.No.: DNAL4-3532H
• Product Overview: Recombinant human DNAL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-105aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: DNAL4 is a component of the dynein motor complex in cells which converts the chemical energy contained in ATP into the mechanical energy of movement. Dynein transports various cellular cargo by "walking" along cytoskeletal microtubules towards the minus-end of the microtubule, which is usually oriented towards the cell center.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
• Molecular Weight: 14.1 kDa(125aa) confirmed by MALDI-TOF
• Purity: >95% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGETEGKKDE ADYKRLQTFP LVRHSDMPEE MRVETMELCV TACEKFSNNN ESAAKMIKET MDKKFGSSWHVVIGEGFGFE ITHEVKNLLY LYFGGTLAVC VWKCS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DNAL4 dynein, axonemal, light chain 4 [ Homo sapiens ]
• Synonyms: DNAL4; PIG27; dynein, axonemal, light chain 4;dynein light chain 4, axonema;dynein, axonemal, light 4;proliferation-inducing gene 27;dynein light chain, outer arm 4;proliferation-inducing protein 27;dynein, axonemal, light polypeptide 4
• Gene ID: 10126
• mRNA Refseq: NM_005740
• Protein Refseq: NP_005731
• MIM: 610565
• UniProt ID: O96015
• Chromosome Location: 22q13.1
• Function: ATPase activity, coupled; microtubule motor activity; microtubule motor activity