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Recombinant Human EFNA4 protein, Fc-tagged

Cat.No. : EFNA4-177H
Product Overview : Recombinant Human EFNA4 (Leu26-Gly171) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293).
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  • Gene Information
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Description : Ephrin-A4 (EFNA4) is also known as EPH-related receptor tyrosine kinase ligand 4 (LERK4), EPLG4, which belongs to the ephrin family. EFNA4 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA4 is cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA4 may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Predicted N Terminal : Leu26
Form : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 43 kDa. The protein migrates as 48 kDa and 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Leu26-Gly171
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : EFNA4
Official Symbol : EFNA4
Synonyms : EFNA4; ephrin-A4; EPLG4; LERK4; LERK-4; ligand of eph-related kinase 4; eph-related receptor tyrosine kinase ligand 4; EFL4; FLJ57652; MGC125826
Gene ID : 1945
mRNA Refseq : NM_005227
Protein Refseq : NP_005218
MIM : 601380
UniProt ID : P52798

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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