Recombinant Human EGF protein

Cat.No.: EGF-08H
Product Overview: Recombinant Human EGF was expressed in Rice Grain.
Description: Human epidermal growth factor, also known as EGF, is a 6 kD protein with 53 amino acid residues and three intramolecular disulfide bonds. By binding with high affinity to epidermal growth fact receptor(EGFR) on the cell surface, EGF results in a variety of biochemical changes within the cell, rising intracelluar calcium levels, increasing glycolysis, protein synthesis and regulating the gene expression, including the gene for EGFR that ultimately lead to DNA synthesis and cell proliferation.
Source: Rice Grain
Species: Human
Form: It is lyophilized with mannitol as the stabilizer.
Bio-activity: >1x10^6 Units/mg.
Endotoxin: < 5 EU/mg
Purity: >95%
Applications: 1. Mammalian cell culture;2. Cosmetic and beauty care
Storage: Stored at - 20 centigrade for at least 12 months. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended to reconstitute the lyophilized the product in strile water. Use as soon as possible after opening.
Shipping: Ice pack
Gene Name: EGF epidermal growth factor [ Homo sapiens ]
Official Symbol: EGF
Synonyms: EGF; epidermal growth factor; epidermal growth factor (beta urogastrone); pro-epidermal growth factor; beta-urogastrone; URG; HOMG4;
Gene ID: 1950
mRNA Refseq: NM_001178130
Protein Refseq: NP_001171601
MIM: 131530
UniProt ID: P01133
Chromosome Location: 4q25
Pathway: Arf6 signaling events, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Ceramide signaling pathway, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem;
Function: calcium ion binding; epidermal growth factor receptor binding; growth factor activity; protein binding; transmembrane receptor protein tyrosine kinase activator activity;

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