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Recombinant Human EGFR protein, His-Avi-tagged
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Cat.No. : | EGFR-258H |
Product Overview : | Human EGFR/HER1 Protein is expressed from mammalian with a His tag and Avi tag at the C-terminal. It contains Leu 25 - Ser645. |
Description : | The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0. 22um filtered solution in PBS (pH 7. 4). |
Molecular Mass : | The protein has a predicted MW of 71. 5 kDa. Due to glycosylation, the protein migrates to 85- 110KDa based on Bis-Tris PAGE result. |
Protein length : | It contains Leu 25 - Ser645. |
Endotoxin : | Less than 0. 05EU per ug by the LAL method. |
Purity : | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
Tris-Bis PAGE : |
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HPLC data : |
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ELISA data : |
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Gene Name : | EGFR epidermal growth factor receptor [ Homo sapiens ] |
Official Symbol : | EGFR |
Synonyms : | ErbB; ErbB1; HER1; HER-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2. 7. 10; EC 2. 7. 10. 1; EGF R; EGFR; epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog); epidermal growth factor receptor; ERBB1PIG61;mENA; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 |
Gene ID : | 1956 |
mRNA Refseq : | NM_005228 |
Protein Refseq : | NP_005219 |
MIM : | 131550 |
UniProt ID : | P00533 |
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◆ Lysates
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