Recombinant Human EGFR protein, His-Avi-tagged

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Recombinant Human EGFR protein, His-Avi-tagged

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Cat.No. : EGFR-258H
Product Overview : Human EGFR/HER1 Protein is expressed from mammalian with a His tag and Avi tag at the C-terminal. It contains Leu 25 - Ser645.
Description : The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
Molecular Mass : The protein has a predicted MW of 71. 5 kDa. Due to glycosylation, the protein migrates to 85- 110KDa based on Bis-Tris PAGE result.
Protein length : It contains Leu 25 - Ser645.
Endotoxin : Less than 0. 05EU per ug by the LAL method.
Purity : > 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

HPLC data :

ELISA data :

Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens ]
Official Symbol : EGFR
Synonyms : ErbB; ErbB1; HER1; HER-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2. 7. 10; EC 2. 7. 10. 1; EGF R; EGFR; epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog); epidermal growth factor receptor; ERBB1PIG61;mENA; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Gene ID : 1956
mRNA Refseq : NM_005228
Protein Refseq : NP_005219
MIM : 131550
UniProt ID : P00533

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