Recombinant Human EGFR protein, His-Avi-tagged EGFR-258H

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Recombinant Human EGFR protein, His-Avi-tagged

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Cat.No. :	EGFR-258H
Product Overview :	Human EGFR/HER1 Protein is expressed from mammalian with a His tag and Avi tag at the C-terminal. It contains Leu 25 - Ser645.
Description :	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses.
Source :	HEK293
Species :	Human
Tag :	His-Avi
Form :	Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
Molecular Mass :	The protein has a predicted MW of 71. 5 kDa. Due to glycosylation, the protein migrates to 85- 110KDa based on Bis-Tris PAGE result.
Protein length :	It contains Leu 25 - Ser645.
Endotoxin :	Less than 0. 05EU per ug by the LAL method.
Purity :	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Storage :	The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :
HPLC data :
ELISA data :

Gene Name :	EGFR epidermal growth factor receptor [ Homo sapiens ]
Official Symbol :	EGFR
Synonyms :	ErbB; ErbB1; HER1; HER-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2. 7. 10; EC 2. 7. 10. 1; EGF R; EGFR; epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog); epidermal growth factor receptor; ERBB1PIG61;mENA; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Gene ID :	1956
mRNA Refseq :	NM_005228
Protein Refseq :	NP_005219
MIM :	131550
UniProt ID :	P00533