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Recombinant Human EGFR protein, His & S-tagged

Cat.No. : EGFR-7629H
Product Overview : Recombinant Human EGFR aa. (Lys713~Asp984 (Accession # P00533)) fused with N-terminal His & S tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Source : E. coli
Species : Human
Tag : His & S
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 37.5kDa
Protein length : Lys713~Asp984 (Accession # P00533)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens (human) ]
Official Symbol : EGFR
Synonyms : ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor receptor
Gene ID : 1956
mRNA Refseq : NM_001346897.1
Protein Refseq : NP_001333826.1
UniProt ID : P00533

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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