Recombinant Human EGFR Protein, His-tagged
Cat.No. : | EGFR-025H |
Product Overview : | Recombinant human EGFR(rhEGFR) Met 1 - Lys 642 (Accession # NP_005219 ) fused with C terminal 6×His tag was expressed in human 293 cells (HEK293). |
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- Gene Information
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Description : | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016] |
Source : | HEK293 cells |
Species : | Human |
Tag : | His |
Molecular Mass : | rhEGFR contains C terminal 6×His Tag and has a calculated MW of 69.5 kDa. The predicted N-terminal is Leu 25. In DTT-reduced SDS-PAGE, protein migrates as 110-115 kDa. |
Endotoxin : | Less than 0.01 ng endotoxin/1 µg rhEGFR. |
Purity : | >95% purity as determined by SDS-PAGE of reduced rhEGFR. |
Notes : | Research Use Only. Not for use in diagnostic or therapeutic procedures. |
Storage : | Store at -20 centigrade in lyophilized state after receipt. For long term storage, upon reconstitution rhEGFR should be aliquot and store at -20 centigrade or -8 centigrade centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Bulk protein in a 0.22 µm filtered solution of PBS, pH 7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization. |
Publication : |
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR (2021)
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Gene Name : | EGFR epidermal growth factor receptor [ Homo sapiens ] |
Official Symbol : | EGFR |
Synonyms : | EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog), ERBB; ERBB1; erythroblastic leukemia viral (v erb b) oncogene homolog (avian); proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; ERBB; HER1; mENA; PIG61; |
Gene ID : | 1956 |
mRNA Refseq : | NM_005228 |
Protein Refseq : | NP_005219 |
MIM : | 131550 |
UniProt ID : | P00533 |
Products Types
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EGFR-0976H | Recombinant Human EGFR Protein (L25-A1210), eGFP, Strep II, 10×His tagged | +Inquiry |
EGFR-339H | Active Recombinant Human EGFR Protein (Leu 25 - Ser 645), Fc-tagged | +Inquiry |
EGFR-212H | Recombinant Human EGFR Protein, Fc-tagged | +Inquiry |
EGFR-1228R | Active Recombinant Rhesus EGFR protein(Met1-Ser645), His-tagged | +Inquiry |
◆ Lysates | ||
EGFR-1621MCL | Recombinant Mouse EGFR cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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