| Cat.No. : |
EPGN-235H |
| Product Overview : |
Recombinant Human EPGN(23-110aa) fused with His tag at C-terminal was expressed in Insect cells. |
| Description : |
EPGN, also known as epigen isoform 1, is a novel member of the epidermal growth factor superfamily. It is the last ligand of ErbB receptors and reveals intricate relationships between affinity and mitogenicity. It stimulated the proliferation of HaCaT cells, and this proliferation was blocked by an antibody to the extracellular domain of the receptor tyrosine kinase c-erbB-1. It also may constitute a novel molecular target for wound-healing therapy with its ability to promote the growth of epithelial cells. It has been reported to have high mitogenic activity but low affinity for its receptor. It has been reported in cancer specimens of the breast, bladder, and prostate. |
| Source : |
Insect cells |
| Species : |
Human |
| Tag : |
His |
| Form : |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Molecular Mass : |
10.8kDa (97aa) 13.5-18kDa (SDS-PAGE under reducing conditions) |
| Protein length : |
23-110aa |
| AA Sequence : |
ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE
KHHHHHH |
| Purity : |
> 90% by SDS - PAGE |
| Applications : |
SDS-PAGE |
| Storage : |
Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.5 mg/ml (determined by Absorbance at 280) |
| Figure : |
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