Recombinant Human ESRRA Protein, MYC/DDK-tagged

• Cat.No.: ESRRA-2222H
• Product Overview: Recombinant human ESRRA protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 45.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ESRRA estrogen-related receptor alpha [ Homo sapiens ]
• Official Symbol: ESRRA
• Synonyms: ERR1; ERRa; ERRalpha; ESRL1; NR3B1
• Gene ID: 2101
• mRNA Refseq: NM_004451
• Protein Refseq: NP_004442
• MIM: 601998
• UniProt ID: P11474