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Recombinant Human ESRRA Protein (1-423 aa), GST-tagged

Cat.No. : ESRRA-2117H
Product Overview : Recombinant Human ESRRA Protein (1-423 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length.
  • Specification
  • Gene Information
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Description : Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.
Source : E. coli
Species : Human
Tag : GST
Form : Tris-based buffer,50% glycerol
Molecular Mass : 72.5 kDa
Protein length : 1-423 aa
AA Sequence : MSSQVVGIEPLYIKAEPASPDSPKG SSETETEPPVALAPGPAPTRCLPGH KEEEDGEGAGPGEQGGGKLVLSSLP KRLCLVCGDVASGYHYGVASCEACK AFFKRTIQGSIEYSCPASNECEITK RRRKACQACRFTKCLRVGMLKEGVR LDRVRGGRQKYKRRPEVDPLPFPGP FPAGPLAVAGGPRKTAAPVNALVSH LLVVEPEKLYAMPDPAGPDGHLPAV ATLCDLFDREIVVTISWAKSIPGFS SLSLSDQMSVLQSVWMEVLVLGVAQ RSLPLQDELAFAEDLVLDEEGARAA GLGELGAALLQLVRRLQALRLEREE YVLLKALALANSDSVHIEDAEAVEQ LREALHEALLEYEAGRAGPGGGAER RRAGRLLLTLPLLRQTAGKVLAHFY GVKLEGKVPMHKLFLEMLEAMMD
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Gene Name : ESRRA estrogen-related receptor alpha [ Homo sapiens ]
Official Symbol : ESRRA
Synonyms : ESRRA; ESRL1; ERR1; ERRa; ERRalpha; NR3B1; ERR-alpha;
Gene ID : 2101
mRNA Refseq : NM_004451
Protein Refseq : NP_004442
MIM : 601998
UniProt ID : P11474

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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