Recombinant Human EXO5 Protein, MYC/DDK-tagged

• Cat.No.: EXO5-2295H
• Product Overview: Recombinant human EXO5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: EXO5 exonuclease 5 [ Homo sapiens ]
• Official Symbol: EXO5
• Synonyms: C1orf176; DEM1; Exo V; hExo5
• Gene ID: 64789
• mRNA Refseq: NM_022774.1
• Protein Refseq: NP_073611.1
• UniProt ID: Q9H790