Recombinant Human FABP2 protein, MYC/DDK-tagged, C13/N15-labeled

• Cat.No.: FABP2-658H
• Product Overview: Recombinant Human FABP2 fused with MYC/DDK tag at C-terminal was expressed in HEK293 and labled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine.

Specification

• Description: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
• Molecular Mass: 15.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Concentration: > 50 ug/ml as determined by BCA

Gene Information

• Gene Name: FABP2 fatty acid binding protein 2, intestinal [ Homo sapiens ]
• Official Symbol: FABP2
• Synonyms: FABP2; fatty acid binding protein 2, intestinal; fatty acid-binding protein, intestinal; I FABP; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; FABPI; I-FABP; MGC133132
• Gene ID: 2169
• mRNA Refseq: NM_000134
• Protein Refseq: NP_000125
• MIM: 134640
• UniProt ID: P12104
• Chromosome Location: 4q28-q31
• Pathway: Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem
• Function: fatty acid binding; long-chain fatty acid transporter activity; transporter activity