Active Recombinant Human FBLN1 Protein, HA-tagged
Cat.No. : | FBLN1-01H |
Product Overview : | Recombinant Human FBLN1 Protein (Asp30-Leu683) with an N-terminal HA tag was expressed in Human embryonic kidney cell, HEK293. |
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Description : | Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. |
Source : | HEK293 |
Species : | Human |
Tag : | HA |
Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of HFL1 human fetal lung fibroblast cells. The ED50 for this effect is 0.7-3.5 μg/mL. |
Molecular Mass : | 73 kDa |
N-terminal Sequence Analysis : | Tyr |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 95% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS |
Reconstitution : | Reconstitute at 250 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | FBLN1 fibulin 1 [ Homo sapiens (human) ] |
Official Symbol : | FBLN1 |
Synonyms : | FBLN1; fibulin 1; FBLN; FIBL1; fibulin-1 |
Gene ID : | 2192 |
mRNA Refseq : | NM_001996 |
Protein Refseq : | NP_001987 |
MIM : | 135820 |
UniProt ID : | P23142 |
Products Types
◆ Recombinant Protein | ||
FBLN1-2429H | Recombinant Human FBLN1 Protein (30-703 aa), His-Myc-tagged | +Inquiry |
FBLN1-723H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
FBLN1-3872H | Recombinant Human FBLN1 Protein, GST-tagged | +Inquiry |
FBLN1-1463H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
FBLN1-1464H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FBLN1-598HCL | Recombinant Human FBLN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFBLN1 has been identified as a potential therapeutic target for the treatment of cardiovascular diseases due to its involvement in vascular function.
Genetic testing for FBLN1 mutations can be helpful in diagnosing certain connective tissue disorders.
The potential side effects of targeting FBLN1 as a therapeutic target are still under investigation and require further clinical trials.
FBLN1 has distinct roles and implications in clinical applications compared to other proteins, making it an important focus of research.
Mutations in the FBLN1 gene have been associated with developmental abnormalities in connective tissues, leading to connective tissue disorders such as Marfan syndrome and cutis laxa.
Customer Reviews (3)
Write a reviewThis partnership enhances research productivity while ensuring accurate and meaningful outcomes.
The manufacturer's commitment to maintaining stringent quality control measures guarantees that I can trust the protein's integrity and reliability throughout my experiments.
Its purity and stability ensure consistent and accurate results, making it an ideal tool for my research endeavors.
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