Recombinant Human FBXL2 Protein, GST-tagged

• Cat.No.: FBXL2-3898H
• Product Overview: Human FBXL2 full-length ORF ( AAH31556, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 72.38 kDa
• AA Sequence: MVFSNNDEGLINKKLPKELLLRIFS FLDIVTLCRCAQISKAWNILALDGS NWQRIDLFNFQTDVEGRVVENISKR CGGFLRKLSLRGCIGVGDSSLKTFA QNCRNIEHLNLNGCTKITDSTCYSL SRFCSKLKHLDLTSCVSITNSSLKG ISEGCRNLEYLNLSWCDQITKDGIE ALVRGCRGLKALLLRGCTQLEDEAL KHIQNYCHELVSLNLQSCSRITDEG VVQICRGCHRLQALCLSGCSNLTDA SLTALGLNCPRLQILEAARCSHLTD AGFTLLARNCHELEKMDLEECILIT DSTLIQLSIHCPKLQALSLSHCELI TDDGILHLSNSTCGHERLRVLELDN CLLITDVALEHLENCRGLERLELYD CQQVTRAGIKRMRAQLPHVKVHAYF APVTPPTAVAGSGQRLCRCCVIL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXL2 F-box and leucine-rich repeat protein 2 [ Homo sapiens ]
• Official Symbol: FBXL2
• Synonyms: FBXL2; F-box and leucine-rich repeat protein 2; F-box/LRR-repeat protein 2; FBL2; FBL3; F-box protein FBL2/FBL3; F-box protein containing leucine-rich repeats; DKFZp564P0622
• Gene ID: 25827
• mRNA Refseq: NM_001171713
• Protein Refseq: NP_001165184
• MIM: 605652
• UniProt ID: Q9UKC9