Recombinant Human FGF2 Protein, His-tagged

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Recombinant Human FGF2 Protein, His-tagged

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Cat.No. : FGF2-001H
Product Overview : Recombinant Human FGF2 Protein (134-288 aa (isoform 18kDa)) with 6xHis tag was expressed in E. coli.
Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : 18.3 kDa
Protein length : 134-288
Purity : >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB).
Applications : ELISA, Western Blot, Antibody Production, Protein array
Quality Control Test : 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6His (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry.
Storage : Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade.
Expiry : All components are stable for 1 year of receipt, if stored properly.
Storage Buffer : Lyophilized from a solution containing 20mM Sodium Phosphate, 0.15M NaCl, 0.5M Imidzole, pH 7,4.
Shipping : Lyophilized at Ambient temperature
Figure :

Gene Name : FGF2 fibroblast growth factor 2 [ Homo sapiens (human) ]
Official Symbol : FGF2
Synonyms : FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2; fibroblast growth factor 2; basic fibroblast growth factor Bfgf; fibroblast growth factor 2 (basic); heparin-binding growth factor 2; prostatropin
Gene ID : 2247
mRNA Refseq : NM_002006
Protein Refseq : NP_001997
MIM : 134920
UniProt ID : P09038

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