Recombinant Human FGF2 Protein, His-tagged
Cat.No. : | FGF2-001H |
Product Overview : | Recombinant Human FGF2 Protein (134-288 aa (isoform 18kDa)) with 6xHis tag was expressed in E. coli. |
Availability | February 16, 2025 |
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Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 18.3 kDa |
Protein length : | 134-288 |
Purity : | >90% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB). |
Applications : | ELISA, Western Blot, Antibody Production, Protein array |
Quality Control Test : | 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6His (WB) and peptide fingerprinting by MALDI-TOF mass spectrometry. |
Storage : | Prior to reconstitution, store the lyophilized protein at 2−8 centigrade. After reconstitution, store in working aliquots at −80 centigrade. |
Expiry : | All components are stable for 1 year of receipt, if stored properly. |
Storage Buffer : | Lyophilized from a solution containing 20mM Sodium Phosphate, 0.15M NaCl, 0.5M Imidzole, pH 7,4. |
Shipping : | Lyophilized at Ambient temperature |
Gene Name : | FGF2 fibroblast growth factor 2 [ Homo sapiens (human) ] |
Official Symbol : | FGF2 |
Synonyms : | FGF2; fibroblast growth factor 2; BFGF; FGFB; FGF-2; HBGF-2; fibroblast growth factor 2; basic fibroblast growth factor Bfgf; fibroblast growth factor 2 (basic); heparin-binding growth factor 2; prostatropin |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006 |
Protein Refseq : | NP_001997 |
MIM : | 134920 |
UniProt ID : | P09038 |
Products Types
◆ Native Protein | ||
FGF2-26551TH | Native Human FGF2 | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
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