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Active Recombinant Human FGF3 Protein, Pre-aliquoted

Cat.No. : FGF3-03H
Product Overview : Recombinant Human FGF3 Protein, Asp28 - Arg212, with an N-terminal Met, was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 0.02-0.1 μg/mL in the presence of 1 μg/mL of heparin.
Molecular Mass : Predicted Molecular Mass:21.1 kDa
Protein length : Asp28-Arg212, with an N-terminal Met
N-terminal Sequence Analysis : Met
Endotoxin : < 0.01 EU/μg of the protein by the LAL method.
Purity : > 97% by SDS-PAGE under reducing conditions and visualized by silver stain.
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• 6 months from date of receipt at room temperature.
• 12 months from date of receipt at 2-8 centigrade as supplied.
• 1 month at 2-8 centigrade under sterile conditions after reconstitution.
• 3 months at -20 to -80 centigrade under sterile conditions after reconstitution.
Reconstitution : For a stock solution, reconstitute at 100 μg/mL in sterile PBS, or simply roll Pre-aliquoted directly to the medium for immediate use.
Shipping : The product is shipped at ambient temperature.
Gene Name : FGF3 fibroblast growth factor 3 [ Homo sapiens (human) ]
Official Symbol : FGF3
Synonyms : FGF3; fibroblast growth factor 3; INT2; HBGF-3; fibroblast growth factor 3; FGF-3; INT-2 proto-oncogene protein; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog); heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; oncogene INT2; proto-oncogene Int-2
Gene ID : 2248
mRNA Refseq : NM_005247
Protein Refseq : NP_005238
MIM : 164950
UniProt ID : P11487

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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