FGF18-224H
Optional Service: Optional requirements on this protein
Product Overview :
The extracellular domain of human FGF-18(AAH06245.1)(Glu28-Ala207) is fused to the N-terminus of the Fc region of a human IgG1was expressed in CHO cell.
Description :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures
Source :
CHO cell
Species :
Human
Tag :
HIgG1 Fc-tagged
Form :
Lyophilized from 0.2 μm-filtered solution in PBS.
Bio-activity :
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration.
Molecular Mass :
47KDa (monomer)
AA Sequence :
Glu28-Ala207
Endotoxin :
<0.06 eu/μg as determined by lal test.>
Purity :
>98%, by SDS-PAGE under reducing conditions
Stability :
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.