- Human(32)
- Mouse(4)
- Rhesus(1)
- Rhesus monkey(4)
Recombinant Human FLT3 Protein, GST-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
| Cat.No. : | FLT3-4370H |
| Product Overview : | Human PDK3 (NP_004110.2, 546 a.a. - 993 a.a.) partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells. |
| Description : | This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq |
| Source : | Insect Cell |
| Species : | Human |
| Tag : | GST |
| Form : | Liquid |
| Bio-activity : | The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000. Substrate: Srctide. ATP: 100 μM. |
| Molecular Mass : | 77 kDa |
| Purity : | 98% by SDS-PAGE/CBB staining |
| Applications : | Functional Study SDS-PAGE |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol) |
| Quality Control Testing : |
Loading 1 μg protein in SDS-PAGE |
| Result of activity analysis : |
|
| Gene Name : | FLT3 fms-related tyrosine kinase 3 [ Homo sapiens ] |
| Official Symbol : | FLT3 |
| Synonyms : | FLT3; fms-related tyrosine kinase 3; receptor-type tyrosine-protein kinase FLT3; CD135; FLK2; STK1; STK-1; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; fms-like tyrosine kinase 3; stem cell tyrosine kinase 1; growth factor receptor tyrosine kinase type III; FLK-2; |
| Gene ID : | 2322 |
| mRNA Refseq : | NM_004119 |
| Protein Refseq : | NP_004110 |
| MIM : | 136351 |
| UniProt ID : | P36888 |
◆ Recombinant Protein
| FLT3-4371H | Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
| FLT3-088H | Recombinant Human FLT3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
| FLT3-2340H | Recombinant Human FLT3 Protein, MYC/DDK-tagged | +Inquiry |
| FLT3-1155R | Recombinant Rhesus Monkey FLT3 Protein, His-tagged | +Inquiry |
| FLT3-1550H | Recombinant human FLT3, Active | +Inquiry |
|
|
◆ Lysates
| FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
| FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
|
|
◆ Assay kits
| Kit-1592 | Flt3 ActivityAssay Kit | +Inquiry |
| Kit-1593 | Flt3 Activity Assay Kit | +Inquiry |
|
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy
