Recombinant Human Forkhead box P3, GST-tagged
Cat.No. : | FOXP3-52H |
Product Overview : | Recombinant Human FOXP3 (1 a.a. - 431 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Cat. No. : | FOXP3-52H |
Description : | The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | Wheat germ |
Molecular Mass : | 73.6 kDa |
Sequence : | MPNPRPGKPSAPSLALGPSPGASPS WRAAPKASDLLGARGPGGTFQGRDL RGGAHASSSSLNPMPPSQL QLPTLPLVMVAPSGARLGPLPHLQA LLQDRPHFMHQLSTVDAHARTPVLQ VHPLESPAMISLTPPTTATGVF SLKARPGLPPGINVASLEWVSREPA LLCTFPNPSAPRKDSTLSAVPQSSY PLLANGVCKWPGCEKVFEEPE DFLKHCQADHLLDEKGRAQCLLQRE MVQSLEQQLVLEKEKLSAMQAHLAG KMALTKASSVASSDKGSCCI VAAGSQGPVVPAWSGPREAPDSLFA VRRHLWGSHGNSTFPEFLHNMDYFK FHNMRPPFTYATLIRWAIL APEKQRTLNEIYHWFTRMFAFFRNH PATWKNAIRHNLSLHKCFVRVESEK GAVWTVDELEFRKKRSQRP SRCSNPTPGP |
Purification : | Glutathione Sepharose 4 Fast Flow |
Storage buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
Applications : | ELISA; WB |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Note : | Best use within three months from the date of receipt of this protein. |
OfficialSymbol : | FOXP3 |
Gene Name : | FOXP3 forkhead box P3 [ Homo sapiens ] |
Synonyms : | FOXP3; forkhead box P3; JM2; AIID; IPEX; PIDX; XPID; DIETER; forkhead box protein P3; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked |
Gene ID : | 50943 |
mRNA Refseq : | NM_014009 |
Protein Refseq : | NP_054728 |
MIM : | 300292 |
UniProt ID : | Q9BZS1 |
Chromosome Location : | Xp11.23 |
Pathway : | Calcineurin-regulated NFAT-dependent transcription in lymphocytes; IL2 signaling events mediated by STAT5 |
Function : | DNA bending activity; NF-kappaB binding; NFAT protein binding; chromatin binding; double-stranded DNA binding |
Products Types
◆ Recombinant Protein | ||
FOXP3-1216H | Recombinant Human FOXP3 Protein, His-tagged | +Inquiry |
FOXP3-938H | Recombinant Human FOXP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Foxp3-3079M | Recombinant Mouse Foxp3 Protein, Myc/DDK-tagged | +Inquiry |
FOXP3-1568R | Recombinant Rhesus Macaque FOXP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FOXP3-2708H | Recombinant Human FOXP3 Protein (Gln105-Lys200), N-His tagged | +Inquiry |
◆ Lysates | ||
FOXP3-6145HCL | Recombinant Human FOXP3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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