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Recombinant Human FOXA2 Protein, GST-tagged

Cat.No. : FOXA2-4433H
Product Overview : Human FOXA2 full-length ORF ( NP_068556.1, 1 a.a. - 457 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 74.7 kDa
AA Sequence : MLGAVKMEGHEPSDWSSYYAEPEGY SSVSNMNAGLGMNGMNTYMSMSAAA MGSGSGNMSAGSMNMSSYVGAGMSP SLAGMSPGAGAMAGMGGSAGAAGVA GMGPHLSPSLSPLGGQAAGAMGGLA PYANMNSMSPMYGQAGLSRARDPKT YRRSYTHAKPPYSYISLITMAIQQS PNKMLTLSEIYQWIMDLFPFYRQNQ QRWQNSIRHSLSFNDCFLKVPRSPD KPGKGSFWTLHPDSGNMFENGCYLR RQKRFKCEKQLALKEAAGAAGSGKK AAAGAQASQAQLGEAAGPASETPAG TESPHSSASPCQEHKRGGLGELKGT PAAALSPPEPAPSPGQQQQAAAHLL GPPHHPGLPPEAHLKPEHHYAFNHP FSINNLMSSEQQHHHSHHHHQPHKM DLKAYEQVMHYPGYGSPMPGSLAMG PVTNKTGLDASPLAADTSYYQGVYS RPIMNSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FOXA2 forkhead box A2 [ Homo sapiens ]
Official Symbol : FOXA2
Synonyms : FOXA2; forkhead box A2; hepatocyte nuclear factor 3, beta, HNF3B; hepatocyte nuclear factor 3-beta; HNF-3B; TCF-3B; HNF-3-beta; forkhead box protein A2; transcription factor 3B; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta; HNF3B; TCF3B; MGC19807;
Gene ID : 3170
mRNA Refseq : NM_021784
Protein Refseq : NP_068556
MIM : 600288
UniProt ID : Q9Y261

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the future research directions for FOXA2? 04/21/2023

Future research directions on FOXA2 include in-depth study of its molecular mechanisms in embryonic development and disease development, the development of targeted drugs targeting FOXA2, and the exploration of its application in regenerative medicine and tissue engineering.

How can the results of FOXA2 be used to advance medicine? 10/22/2022

The results of FOXA2 research can be used to advance medicine, such as developing diagnostic and therapeutic strategies for developmental defects and tumors, exploring new drug targets, and improving existing treatment options. At the same time, these research results can also be applied to regenerative medicine and tissue engineering for the repair of damaged tissues and organs.

What are the molecules that interact with FOXA2? 04/09/2022

Molecules that interact with FOXA2 include other transcription factors, co-activators, co-repressors, etc. These molecules, together with FOXA2, regulate the expression of downstream genes.

How can I study the features of FOXA2? 11/17/2021

A variety of experimental methods can be used to study the function of FOXA2, including gene knockout, overexpression, chromatin immunoprecipitation (ChIP), reporter gene analysis, and more. These methods can help us gain insight into the role of FOXA2 in embryonic development and disease development.

Does FOXA2 have a function in embryonic development? 01/14/2021

FOXA2 plays a key role in embryonic development and is involved in regulating processes such as endoderm formation, differentiation of the pancreas and lungs, and development of the digestive tract.

How do you assess the quality and reliability of research results for FOXA2? 01/23/2020

Assessing the quality and reliability of scientific research results for FOXA2 requires the use of scientific methods and standards, including the rationality of experimental design, the accuracy of data processing, and the logic and reproducibility of conclusions. In addition, peer review and quality assessment of papers published in high-level academic journals are required.

Customer Reviews (3)

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Reviews
03/21/2023

    FOXA2 has strong anti-fouling ability, which effectively avoids the problem of contamination in the experiment.

    05/16/2022

      It has good application performance in immunoassays, such as ELISA, western blotting, etc.

      06/25/2021

        This protein has good fluorescence and absorption properties.

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