Recombinant Human FOXP3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FOXP3-720H
• Product Overview: FOXP3 MS Standard C13 and N15-labeled recombinant protein (NP_054728) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 47.1 kDa
• AA Sequence: MPNPRPGKPSAPSLALGPSPGASPS WRAAPKASDLLGARGPGGTFQGRDL RGGAHASSSSLNPMPPSQLQLPTLP LVMVAPSGARLGPLPHLQALLQDRP HFMHQLSTVDAHARTPVLQVHPLES PAMISLTPPTTATGVFSLKARPGLP PGINVASLEWVSREPALLCTFPNPS APRKDSTLSAVPQSSYPLLANGVCK WPGCEKVFEEPEDFLKHCQADHLLD EKGRAQCLLQREMVQSLEQQLVLEK EKLSAMQAHLAGKMALTKASSVASS DKGSCCIVAAGSQGPVVPAWSGPRE APDSLFAVRRHLWGSHGNSTFPEFL HNMDYFKFHNMRPPFTYATLIRWAI LEAPEKQRTLNEIYHWFTRMFAFFR NHPATWKNAIRHNLSLHKCFVRVES EKGAVWTVDELEFRKKRSQRPSRCS NPTPGPTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FOXP3 forkhead box P3 [ Homo sapiens (human) ]
• Official Symbol: FOXP3
• Synonyms: FOXP3; forkhead box P3; immune dysregulation, polyendocrinopathy, enteropathy, X linked, IPEX; forkhead box protein P3; AIID; DIETER; JM2; PIDX; SCURFIN; XPID; scurfin; FOXP3delta7; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; IPEX; MGC141961; MGC141963
• Gene ID: 50943
• mRNA Refseq: NM_014009
• Protein Refseq: NP_054728
• MIM: 300292
• UniProt ID: Q9BZS1