Recombinant Human FTH1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FTH1-1941H
• Product Overview: FTH1 MS Standard C13 and N15-labeled recombinant protein (NP_002023) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 21.2 kDa
• AA Sequence: MTTASTSQVRQNYHQDSEAAINRQI NLELYASYVYLSMSYYFDRDDVALK NFAKYFLHQSHEEREHAEKLMKLQN QRGGRIFLQDIKKPDCDDWESGLNA MECALHLEKNVNQSLLELHKLATDK NDPHLCDFIETHYLNEQVKAIKELG DHVTNLRKMGAPESGLAEYLFDKHT LGDSDNESTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FTH1 ferritin heavy chain 1 [ Homo sapiens (human) ]
• Official Symbol: FTH1
• Synonyms: FTH1; ferritin, heavy polypeptide 1; FTHL6; ferritin heavy chain; apoferritin; FHC; FTH; PIG15; placenta immunoregulatory factor; PLIF; proliferation inducing protein 15; ferritin H subunit; proliferation-inducing protein 15; cell proliferation-inducing gene 15 protein; MGC104426
• Gene ID: 2495
• mRNA Refseq: NM_002032
• Protein Refseq: NP_002023
• MIM: 134770
• UniProt ID: P02794