Human FTH1 Knockdown Cell Lysate

• Cat.No.: FTH1-167HKCL
• Product Overview: WB-validated FTH1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 21 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg FTH1 KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Porphyrin and chlorophyll metabolism
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: FTH1 ferritin, heavy polypeptide 1 [ Homo sapiens (human) ]
• Official Symbol: FTH1
• Synonyms: FTH1; ferritin, heavy polypeptide 1; FTHL6; ferritin heavy chain; apoferritin; FHC; FTH; PIG15; placenta immunoregulatory factor; PLIF; proliferation inducing protein 15; ferritin H subunit; proliferation-inducing protein 15; cell proliferation-inducing gene 15 protein; MGC104426
• Gene ID: 2495
• mRNA Refseq: NM_002032
• Protein Refseq: NP_002023
• MIM: 134770
• UniProt ID: P02794